Skip to main content

Advertisement

Table 3 BOLD responses from both our anatomical ROI analyses and our functional ROI analyses comparing males and women during the different phases of the study

From: Sex differences in the neurobiology of fear conditioning and extinction: a preliminary fMRI study of shared sex differences with stress-arousal circuitry

Bold responses from anatomical ROI analyses
Phase condition regions coordinates z P(≤)
conditioning F > M L-dACC −8,38,26 3.54 0.001
   R-rACC 12,58,4 3.44 0.001
   Amyg 28,-6,-16 3.08 0.001
  M > F non    
Ext learning F > M non    
  M > F non    
Ext Recall F > M L-insula −46,-2,-10 3.15 0.002
  M > F L-rACC −6,32,-4 2.79 0.005
BOLD responses from functional ROI analyses
Conditioning F > M non    
  M > F non    
Ext Learning F > M dACC 8,12,18 3.62 0.001
   dACC 10,14,20 3.27 0.001
   mPFC 28,54,-4 3.33 0.001
   L-hypotha −8,2,-6 2.25 0.024
  M < F hypothalamus 6,4,-6 2.44 0.015
Ext Recall F > M non    
  M > F L-rACC −6,42,-16 3.16 0.001
  1. ROIs are based on sexually dimorphic areas of the stress response circuitry identified by Goldstein and colleagues (2010).