Differences between men and women in psychophysiological and BOLD measures during fear acquisition. A. Skin conductance responses (SCR) averaged across the first 4 conditioning trials for the conditioned stimulus that was reinforced, i.e. paired with the shock (CS+) and for the conditioned stimulus not paired with the shock (CS-). B. BOLD activation to the CS + vs. CS- contrasting Females vs. Males during fear conditioning is shown. C. Mean beta weights extracted from the dorsal anterior cingulate cortex (dACC), rostral anterior cingulate (rACC), and amygdala are shown, to illustrate the direction of activation within group. The threshold display for the maps in B is p < 0.01, uncorrected. M = males; F = females.