Erratum to: Somatic therapies for treatment-resistant depression: ECT, TMS, VNS, DBS
© Cusin and Dougherty; licensee BioMed Central Ltd. 2013
Received: 7 December 2012
Accepted: 13 December 2012
Published: 1 January 2013
The original article was published in Biology of Mood & Anxiety Disorders 2012 2:14
The NIH-sponsored large multicenter trial  was published in 2010, not 2009. Also, note that the primary outcome measure of this study was remission, not response (as was the case in the Neuronetics study ). Most important, we erroneously reported that most remitters had low antidepressant resistance. In fact, the relationship between remission and treatment resistance was not significant. Also, the study cohort had an average of 1.5 failed research-quality adequate treatment trials (by Antidepressant Treatment History Form [ATHF] criteria), which translates approximately to 3 to 6 clinical medication trials, in the current episode and an average of 3.3 failed research-quality adequate treatment trials (approximately 9 clinical attempts) during their lifetimes. In conclusion, the data from George et al.  support the efficacy of TMS for TRD.
We were also provided a link (http://www.effectivehealthcare.ahrq.gov/search-for-guides-reviews-and-reports/?pageaction=displayproduct&productid=787) from the Agency for Healthcare Research and Quality (a division of the US Department of Health and Human Services) website that was not identified during our PubMed search. This review of primary data found that TMS demonstrates greater efficacy than sham control for TRD and found no statistically significant differences in depression severity and response rate in published studies directly comparing TMS to ECT.
We appreciate these comments from the readers and concur that, contrary to what is stated in our initial article, that there is substantial evidence supporting the efficacy of TMS for TRD.
- Cusin C, Dougherty DD: Somatic therapies for treatment-resistant depression: ECT, TMS, VNS, DBS. Biol Mood Anxiety Disord. 2012, 2 (1): 14-10.1186/2045-5380-2-14.PubMed CentralView ArticlePubMedGoogle Scholar
- George MS, Lisanby SH, Avery D, McDonald WM, Durkalski V, Pavlicova M, Anderson B, Nahas Z, Bulow P, Zarkowski P, et al: Daily left prefrontal transcranial magnetic stimulation therapy for major depressive disorder: a sham-controlled randomized trial.
- O'Reardon JP, Solvason HB, Janicak PG, Sampson S, Isenberg KE, Nahas Z, McDonald WM, Avery D, Fitzgerald PB, Loo C, et al: Efficacy and safety of transcranial magnetic stimulation in the acute treatment of major depression: a multisite randomized controlled trial.
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