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Fig. 4 | Biology of Mood & Anxiety Disorders

Fig. 4

From: Intolerance of uncertainty predicts fear extinction in amygdala-ventromedial prefrontal cortical circuitry

Fig. 4

Intolerance of uncertainty predicts vmPFC activation during fear extinction. a vmPFC small volume correction from the (CS− > CS+)early > (CS− > CS+)late × IU contrast in extinction. b Significant correlations between percent signal change in the vmPFC for CS+ − CS− and IU scores during early and late extinction. During late extinction, high IU scores were associated with increased recruitment of the vmPFC to the CS+, relative to the CS−, suggesting attempts to down regulate fearful associations. MNI coordinates: R right, L left

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