Structural abnormality of the corticospinal tract in major depressive disorder

Table 4 Group differences in FA in AFQ-identified fiber tracts

AFQ fiber group	CTL FA		MDD FA		pvalue
AFQ fiber group	M	SD	M	SD	pvalue
Left corticospinal tract	0.620	0.020	0.644	0.020	<0.002
Right corticospinal tract	0.614	0.021	0.639	0.015	<0.001

p values were computed using two-sample t-tests and a false discovery rate (FDR) procedure was used to account for false positives as a result of multiple comparisons. See Figure 1 for corticospinal tract (CST) renderings and graphical display of differences.
AFQ automated fiber quantification, MDD major depressive disorder, CTL control, FA fractional anisotropy, M mean, SD standard deviation.

ISSN: 2045-5380