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Table 3 Between-group differential BOLD responses for React versus Asterisks in 27 patients with SAD versus 27 HC

From: Is there less to social anxiety than meets the eye? Behavioral and neural responses to three socio-emotional tasks

Brain regions

x y z

Vol (mm3)

t-value

Faces

   

SAD > HC

   

Medial Frontal Gyrus

0, 62, 8

2235

4.4

Superior Medial Frontal Gyrus

0, 52, 36

447

3.2

Left Medial Frontal Gyrus

−7, 59, -2

244

3.33

 

−14, 52, 1

203

3.21

Left Middle Frontal Gyrus

−28, 52, 5

162

3.12

 

−28, 49, 12

284

3.11

Left Middle Temporal Gyrus

−52, 14, -12

325

3.6

Right Superior Temporal Gyrus

52, -61, 19

406

3.03

Criticism

   

SAD > HC

   

Left Lingual Gyrus

−24, -75, -9

244

3.13

 

−17, -82, 5

162

2.96

Left Middle Temporal Gyrus

−52, 0, -16

203

3.45

Right Middle Temporal Gyrus

48, -10, -16

203

3.71

Right Parahippocampus

14, -10, -16

162

3.23

Beliefs

   

SAD > HC - none

   

HC > SAD

   

Right Middle Frontal Gyrus

52, 38, 36

244

3.19

Left Superior Temporal Gyrus

−69, -27, 12

162

3.46

  1. Note. t-value threshold ≥ 2.932, voxel P < 0.005, minimum cluster volume threshold ≥162 mm3 (4 voxels x 3.438 mm3), cluster P < 0.01.
  2. BA = Brodmann area, xyz = Talairach and Tournoux coordinates of maximum BOLD signal intensity voxel.