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Figure 6 | Biology of Mood & Anxiety Disorders

Figure 6

From: Brain white matter microstructure alterations in adolescent rhesus monkeys exposed to early life stress: associations with high cortisol during infancy

Figure 6

Maltreated animals have reduced fractional anisotropy (FA) in left occipital white matter (WM) (left occipital cluster 2). (A) Cluster of voxels (red) in left occipital WM where maltreated animals had significantly lower FA than controls (P < 0.005, uncorrected, ≥ 10 μL volume). In insets, green represents the mean FA skeleton. (B) FA in left occipital WM is negatively correlated with basal cortisol at one month of age (r = −0.479, P = 0.038). (C) FA in left occipital WM is negatively correlated with total aggression in adolescence (r = −0.465, P = 0.045).

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