Criteria of validity for animal models of psychiatric disorders: focus on anxiety disorders and depression

Table 1 Criteria for animal models of depression and of anxiety disorders

Reference	N	Predictive validity	Face validity	Construct validity	Others
[12]	8	Specificity			Efficiency Speed Simplicity Reproducibility Adequate design Adequate data processing Correlation with other tests
[13]	5	Similar response to treatments	Analogy of symptoms		Observable and measurable behavioral changes Interobserver agreement Reproducibility of the system
[14]	4	Is the model thorough in describing features of its cures? Similarity of cure	Symptoms similarity	Is the model thorough in describing features of its cause? Similarity of physiology, cause	Does model describe the disorder or a sub-category? Is the model thorough in describing features of its prevention? Similarity of prevention
[17]	3	Predictability	Isomorphism	Homology
[9]	6	Predictive validity	Face validity	Construct validity	Reliability Etiological validity Convergent validity Discriminant validity
[28]	3	Predictive	Face	Construct
[18]	6	Predictive	Face	Etiological validity Construct validity	Convergent validity Reliability
[19]	3	Predictive	Face	Construct

The criteria proposed by various authors are compared to the three criteria elaborated by Willner (1994) [15]. N: number of proposed criteria.

ISSN: 2045-5380