From: An fMRI study of unconditioned responses in post-traumatic stress disorder
Contrast
ROIa | MNIb, peak x, y, z | Z-score | Size, voxels | Cluster Pvalue, FWEc | Region |
---|---|---|---|---|---|
US d | |||||
PTSDe > TENCf | |||||
Whole brain | -22, 0, -6 | 5.51 | 111 | < 0.0001 | Left putamen |
(-24, 10, -14) | -5.47 | ||||
(-32, 2, -4) | -4.93 | ||||
18, 10 -12 | 5.47 | 90 | < 0.0001 | Right putamen | |
(20, 10, -4) | -5.13 | ||||
-22, -4, 48 | 5.25 | 19 | 0.003 | Left middle frontal gyrus | |
-18, -38, -4 | 5.07 | 11 | 0.007 | Left parahippocampal gyrus | |
Putamen | 16, 12, -10 | 5.34 | 359 | < 0.0001 | Right ventral putamen |
(30, -20, 6) | -3.79 | ||||
(28, -2, -6) | -3.73 | ||||
-26, 2, -4 | 5.11 | 840 | < 0.0001 | Left putamen | |
(-22, 8, -10) | -4.88 | ||||
(-32, -12, -6) | -4.75 | ||||
Amygdala | -22, 6, -16 | 4.3 | 48 | 0.01 | Left amygdala |
24, 2, -16 | 4.27 | 81 | 0.005 | Right amygdala | |
Hippocampus | -18, -32, 4 | 4.43 | 36 | 0.029 | Left hippocampus |
(-22, -24, -8) | -3.74 | ||||
-26, -34, 8 | 3.79 | 18 | 0.028 | Left hippocampus | |
(-14, -32, 10) | -3.52 | ||||
-26, -12, -12 | 3.69 | 25 | 0.042 | Left hippocampus | |
(-20, -4, 12) | -3.62 | ||||
Cingulate | 8, 12, 42 | 3.8 | 19 | 0.013 | Right dorsal acc |
Insula | 34, -20, 4 | 4.97 | 36 | 0.006 | Right posterior insula |
-26, 14, -16 | 5.05 | 28 | 0.008 | Left piriform insula | |
-34, -6, 16 | 4.14 | 13 | 0.017 | Left middle insula | |
-36, -22, 4 | 4.08 | 17 | 0.014 | Left posterior insula | |
Caudate | -14, 16, -8 | 4.2 | 67 | 0.006 | Right caudate |
(16, 18, 0) | -3.81 | ||||
16, 0, 16 | 3.86 | 24 | 0.021 | Right caudate | |
-12, 10, 14 | 4.41 | 297 | 0.001 | Left caudate body | |
(-18, -2, 22) | -4.16 | ||||
TENC > PTSD | No significant differences in whole brain or ROI | ||||
Omitted US | |||||
PTSD > TENC | |||||
Whole brain | No significant differences in whole brain | ||||
Hippocampus | 22, -10, -20 | 3.77 | 54 | 0.009 | Right anterior hippocampus |
(30, -10, -18) | -3.46 | ||||
TENC > PTSD | No significant differences in whole brain or ROI | ||||
US minus omitted US | |||||
PTSD > TENC | |||||
Whole brain | No significant differences in whole brain | ||||
Putamen | 20, 12, -10 | 3.89 | 69 | 0.003 | Right ventral putamen |
20, 0, 12 | 3.48 | 13 | 0.032 | ||
Insula | -28, 16, -18 | 4.05 | 52 | 0.016 | Left orbital insula |