20 Israeli combat veterans with PTSD|
20 without PTSD
Modified target detection visual oddball paradigm, trauma related|
Accentuated P300 amplitudes to target stimuli in both controls and PTSD patients|
Enhanced P300 amplitude in response to non-target combat related pictures in PTSD group
Prolonged P300 latencies and reaction times to target stimuli were prolonged in PTSD subjects
Increased latency in response to trauma-related stimuli in PTSD subjects
20 Israeli veterans with PTSD|
20 without PTSD
Modified target detection visual oddball paradigm, trauma related,|
unrelated, neutral pictures
Smaller response to non-target images in the control, but equal responses to both target and non-target stimuli in the PTSD group|
No group difference for the target stimuli, but larger response to the non-target in the PTSD group.
P300 could correctly classify 90% of PTSD and 90% of non-PTSD subjects.
Increased latency of P300 response to combat-related images in relation with the severity of intrusive symptoms.
This relation was negative between the P300 latency and severity of avoidance.
20 PTSD combat veterans|
20 non-PTSD combat veterans
|Target detection oddball, traumatic/neutral stimuli||
Larger P300 amplitude in the PTSD group|
No difference inP300 amplitude between the target and non-target in the PTSD group; higher amplitude in response to the target stimuli in the control group.
Earlier and 5 times greater P300 response to combat related pictures in PTSD patients.
Repeated combat related pictures resulted in a rapid P300 amplitude reduction and latency prolongation. This effect was not observed for the target stimuli.
19 civil PTSD|
17 subjects with numerous life events
18 without life events
|Auditory oddball||Longer reaction times and lower amplitude P300 response|
8 non-PTSD combat veterans
|Visual presentation of a sequence of trauma related and unrelated words||Newly identified P300tr component was suppressed to all stimuli in PTSD subjects|
34 PTSD [25 male veterans/9 female victims of rape]|
18 non-PTSD [10/8 from the same groups]
|Auditory three-tone oddball||Smaller P300 response to the target tone. For women group, it was also smaller in response to the distracter tones.|
9 PTSD [assault, rape, MVA, combat]|
10 healthy controls
|Modified stroop paradigm, visual presentation of neutral, positive and negative words||
Smaller P300 amplitude to neutral, positive, and negative words in PTSD patients.|
Smaller response to neutral words as compared to positive and negative words.
16 medicated PTSD|
9 un-medicated PTSD
10 healthy veterans
|Auditory three-tone oddball||
Significant decrease in P300 at Pz electrode in un-medicated PTSD group compared to the medicated PTSD and healthy subjects.|
Subjects with co-morbid panic disorder had the largest P300 amplitudes.
11 survivors of a ship fire with PTSD or near PTSD|
9 controls with other psychiatric illnesses from the same ship
|Auditory word and non-word oddball||Reduced P300 amplitude to non-words and negative words|
|||25 combat veterans with PTSD/14 without PTSD||Auditory three-tone oddball||
Reduced P300 amplitude to the target stimuli.|
Significant P300 amplitude enhancements at frontal sites to distracting stimuli during the novelty but not during the three-tone oddball tasks.
10 Vietnam war veterans with PTSD|
10 without PTSD
|Two oddball tasks of visual trauma-relevant and trauma-irrelevant threat (combat, social-threat, household, and neutral words)||
Attenuated P300 response to neutral target stimuli|
Increased P300 amplitude in response to trauma-relevant combat stimuli but not to trauma-irrelevant social-threat stimuli at frontal electrode sites.
17 civil PTSD|
17 healthy controls
|Auditory oddball||Smaller P300 in PTSD, later at Pz|
29 PTSD nurse veterans|
|Three-tone oddball||Larger target P300 amplitudes in PTSD subjects|
15 civil PTSD|
|20 angry and 20 neutral faces||Slower P270 in the PTSD at occipital electrodes|
25 combat PTSD|
15 combat-exposed healthy controls
|Three conditioned novelty visual and auditory oddball||No significant differences in P300 amplitude or latency regardless of stimulus type (target, novel) or modality (auditory, visual).|
10 civil PTSD|
|Auditory oddball||Same P3a amplitude in both groups, but there was a significant post-treatment attenuation of P3a in the PTSD group.|
8 PTSD victims of Tokyo sarin attack|
13 healthy controls
No difference in P300 latency.|
Significantly smaller P300 amplitudes in subjects with PTSD.
33 civil PTSD|
33 matched controls
|Auditory standard two-tone oddball||Delayed reduced P300 target amplitude, coupled with slower and less accurate target detection|
10 male police/veteran PTSD|
10 healthy controls
More false negatives and positives;
The higher the anxiety and depression level, the lower the amplitude;
Reverse relationship between the P550 amplitude and intrusions.
99 Alcohol dependence
16 personality disorder
25 anxiety or mood disorder
|Visual presentation of happy, sad, and neutral faces||
Longer P300 latency to happy stimuli in midline, central, and right frontal leads;|
Reduced P300 amplitude in response to neutral faces.
16 civil PTSD|
15 trauma-exposed without PTSD
16 healthy controls
|Modified auditory S1-S2 paradigm||
Increased P300 and late positive complex amplitudes to trauma-specific questions;|
Only the PTSD group showed a differentiation between trauma-specific and neutral questions with respect to P300.
14 PTSD survivors of an air show disaster|
15 trauma-exposed subjects without PTSD
15 healthy controls
|Visual differential conditioning paradigm with traumatic/neutral pictures||Trauma-exposed subjects with and without PTSD showed successful differential conditioning to the trauma-relevant cue indicative of second-order conditioning|
16 civil PTSD|
16 control subjects
Reduced amplitude of target and non-target P300 responses.|
Larger reduction in target P300 amplitude in left posterior parietal leads in PTSD group.
|||37 combat exposed veterans with PTSD and 47 without PTSD and their twins||Auditory oddball||No difference in P300 amplitude; When assessed the un-medicated nonsmoker group separately, P300 amplitude was smaller in the PTSD group|
20 un-medicated and 14 medicated PTSD [mixed etiology]|
|1-back working memory task||
Reduced P300 working memory amplitude and delayed target P300 in PTSD.|
Amplitude reduction and delay of target P300 in medicated PTSD subjects.
Little difference between the non-medicated PTSD subgroup and the controls.
|||12 PTSD and 12 control survivors of earthquake||Subliminal visual presentation of earthquake-related/unrelated words||Increased P2 and P3 amplitude in the PTSD group in response to the trauma-related stimuli|