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Figure 1 | Biology of Mood & Anxiety Disorders

Figure 1

From: Aberrant amygdala functional connectivity at rest in pediatric anxiety disorders

Figure 1

Between-group whole-brain voxel-wise statistical t map of a priori hypothesized group differences overlaid on a canonical brain rendering showing: (A) greater right amygdala connectivity to the insula (anxiety disorder (AD) group > healthy control (HC) group; and (B) decreased amygdala connectivity to the medial prefrontal cortex (mPFC) and posterior cingulate cortex (PCC) (AD < HC). Statistical t map thresholded at whole-brain voxel-wise (p < 0.005, cluster volume > 352 mm3, representing corrected α < 0.05); color bar represents statistical t scores. Bar graph shows mean extracted parameter estimate β weights in arbitrary units (±SEM) within each group from 10 mm spherical region of interest surrounding peak.

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