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Table 2 White matter clusters with reduced fractional anisotropy (FA) in pediatric OCD patients versus healthy controls

From: Brain white matter integrity and association with age at onset in pediatric obsessive-compulsive disorder

Cluster label and anatomical localization Voxels MNI coordinates FA
   x y z OCD HC p
1. Bilateral frontal (ATR, UF, IFOF, forceps minor, anterior corona radiata) and corpus callosum (genu, body, splenium) 9,022 20 37 6 0.533 ± 0.191 0.573 ± 0.188 0.026
2. Right cingulate and basal ganglia: anterior cingulate cortex (UF), anterior limb of IC (ATR), putamen (UF), amygdala (ILF), cerebral peduncle (CST), thalamus, and posterior limb of IC (ATR) 1,454 23 0 −9 0.419 ± 0.157 0.460 ± 0.158 0.035
3. Right posterior cerebral cortex: lateral occipital and angular gyri (SLF) 132 36 −56 33 0.423 ± 0.100 0.500 ± 0.098 0.048
4. Right inferior frontal lobe (subcallosal cortex) 50 8 21 −19 0.296 ± 0.067 0.370 ± 0.107 0.049
5. Right inferior frontal: orbitofrontal cortex 36 8 37 −22 0.267 ± 0.067 0.323 ± 0.073 0.050
6. Right thalamus 14 18 −5 11 0.639 ± 0.041 0.668 ± 0.038 0.050
7. Right caudate, anterior IC (ATR) 6 22 −4 24 0.430 ± 0.056 0.493 ± 0.081 0.050
  1. ATR anterior thalamic radiation, CST corticospinal tract, IC internal capsule, IFOF inferior fronto-occipital fasciculus, ILF inferior longitudinal fasciculus, SLF superior longitudinal fasciculus, UF uncinate fasciculus.