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Figure 4 | Biology of Mood & Anxiety Disorders

Figure 4

From: Reduced hippocampal and medial prefrontal gray matter mediate the association between reported childhood maltreatment and trait anxiety in adulthood and predict sensitivity to future life stress

Figure 4

mPFC gray matter volume mediates the relationship between childhood maltreatment and trait anxiety in adulthood. Results from a path analysis testing a model wherein mPFC gray matter volume mediates the relationship between childhood maltreatment and trait anxiety in adulthood. Values represent standardized parameter estimates with standard errors presented in parentheses after controlling for age, gender, and recent life stress (LESS). The circles labeled e1 and e2 denote the variance in mPFC gray matter volume and trait anxiety scores unaccounted for by the model. *p <0.05, **p <0.005.

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