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Figure 7 | Biology of Mood & Anxiety Disorders

Figure 7

From: Brain white matter microstructure alterations in adolescent rhesus monkeys exposed to early life stress: associations with high cortisol during infancy

Figure 7

Maltreated animals have reduced fractional anisotropy (FA) in white matter (WM) dorsal to the hippocampus and lateral to the pulvinar nucleus. (A) Cluster of voxels (red) where maltreated subjects had significantly lower FA than controls (P < 0.005, uncorrected, ≥ 10 μL) seems to correspond to the external medullary lamina (EML). In insets, green represents the mean FA skeleton. (B) FA in the EML is negatively correlated with basal cortisol at one month of age (r = −0.637, P = 0.003).

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