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Table 1 Neural activation decrease over time in the phobic group

From: Individual differences in cognitive reappraisal usage modulate the time course of brain activation during symptom provocation in specific phobia

Structure

H

x

y

z

Zmax

pfwe

Phobia gt neutral

      

Middle temporal gyrus

L

−45

14

−29

4.92

.029E

insula

L

−30

20

−8

3.30

.069+

caudate nucleus

R

21

−16

22

3.45

.037

dlPFC

L

−24

32

46

3.74

.071+

dmPFC

L

−6

29

40

4.79

.001

.050E+

dmPFC

L

−3

53

7

3.99

.017

dmPFC

R

6

47

4

4.33

.004

dmPFC

R

6

32

43

3.33

.098+

rACC

L

−3

50

7

4.00

.006

rACC

R

6

44

4

3.87

.009

vlPFC

L

−39

29

13

4.14

.011

vlPFC

L

−45

17

13

3.57

.071+

vmPFC

L

−3

56

−11

4.05

.008

vmPFC

R

9

59

−14

3.76

.021

Neutral gt phobia

      

no significant results

      

Phobia gt fear

      

insula

L

−39

−1

4

3.18

.097+

vlPFC

L

−45

8

10

3.94

.023

vlPFC

R

48

17

1

3.57

.076+

Fear gt phobia

      

no significant results

      

Phobia gt disgust

      

rACC

R

6

38

13

3.94

.031

Disgust gt phobia

      

vmPFC

R

9

29

−23

3.57

.034

vmPFC

R

3

23

−23

3.52

.039

  1. Neural activation decrease over the course of symptom provocation for phobic compared with neutral pictures for exploratory whole brain analyses (marked with E) and regions of interest analyses (pfwe < .05); tendentially significant results pfwe < .1 are marked with +; all coordinates (x, y, z) are given in MNI space. H, hemisphere; L, left R, right; Z max , maximum Z-value p fwe , fwe-corrected p-value (small-volume correction).