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Table 2 Number of activation foci included in between-group analyses

From: Quantitative meta-analysis of neural activity in posttraumatic stress disorder

Study

P > C+

C > P+

Statistical threshold

Symptom Provocation Whole Brain Analyses

Bremner et al. 1999a

5

5

P < .001

Bremner et al. 1999b

9

19

P < .001

Britton et al. 2005

--

1

P < .005

Hou et al. 2007

1

9

P < .005

Lanius et al. 2001

--

4

P < .001

Lanius et al. 2002

9

3

P < .001, > 10 voxels

Lanius et al. 2003

--

9

P < .001, > 10 voxels

Lanius et al. 2007

--

2

P < .05 cor., > 10 voxels

Shin et al. 1999

4

14

P < .001

Shin et al. 2004

1

3

P < .001

Symptom Provocation ROI Analyses

Protopopescu et al. 2005

1

--

P < .01 cor.

Frewen et al. 2008

--

3

P < .05, > 10 voxels

Cognitive-Emotional Whole Brain Analyses

Bremner et al. 2003

15

14

P < .01 cor.

Bremner et al. 2004

2

6

P < .005 cor., > 65 voxels

Brunetti et al. 2010

6

3

P < .001

Felmingham et al. 2010

1

--

P < .001, > 10 voxels

Fonzo et al. 2010

3

1

P < .05

Kim et al. 2007

7

6

P < .001

Sakamoto et al. 2005

1

4

P < .01

Shin et al. 2005

4

4

P < .001

Thomaes et al. 2009

2

--

P < .001

Whalley et al. 2009

3

1

P < .001

Williams et al. 2006

7

1

P < .001

Hou et al. 2007*

--

2

P < .005

Cognitive-Emotional ROI Analyses

Bryant et al. 2008

4

--

P < .05, > 3 voxels

Phan et al. 2006

--

1

P < .005 cor.

Rauch et al. 2000

1

--

P < .05

Felmingham et al. 2010**

9

--

P < .001, > 10 voxels

Fonzo et al. 2010**

2

--

P < .05

Williams et al. 2006**

2

4

P < .001

Total SP foci

30

72

 

Total cognitive-emotional foci

69

47

 

Total number of foci

99

119

 
  1. +P > C: PTSD patients > Controls; C > P: Controls > PTSD patients.
  2. *Paper also reported symptom provocation coordinates.
  3. **Papers also reported whole brain coordinates.
  4. cor. = corrected for multiple comparisons.