From: Quantitative meta-analysis of neural activity in posttraumatic stress disorder
Study | PTSD | TC* | NTC** | Type of trauma | Contrast used in meta-analysis | Scanning task | Imaging method | Design |
---|---|---|---|---|---|---|---|---|
Symptom Provocation Whole Brain Analyses (10) | ||||||||
Bremner et al. 1999a | 10 | 10 | Â | Combat | Combat vs. neutral pictures and sounds | View and listen | PET | Block |
Bremner et al. 1999b | 10 | 12 | Â | SA+ | Childhood abuse vs. neutral scripts | Image and remember event | PET | Block |
Britton et al. 2005 | 16 | 15 | Â | Combat | Combat vs. neutral scripts | Listen and maintain evoked emotional state | PET | Block |
Hou et al. 2007 | 10 | 7 | Â | Mining accident | Mining accident vs. neutral pictures | View | fMRI | Block |
Lanius et al. 2001 | 9 | 9 | Â | Mixed | Trauma scripts vs. baseline | Listen and remember event | fMRI | Block |
Lanius et al. 2002 | 7 | 10 | Â | SA (1 MVA) + | Trauma scripts vs. baseline | Listen and remember event | fMRI | Block |
Lanius et al. 2003 | 10 | 10 | Â | Mixed | Trauma scripts vs. baseline | Listen and remember event | fMRI | Block |
Lanius et al. 2007 | 26 | 16 | Â | MVA+ | Trauma vs. neutral scripts | Listen and remember event | fMRI | Block |
Shin et al. 1999 | 8 | 8 | Â | SA+ | Sexual abuse vs. neutral scripts | Recall and imagine contents of script | PET | Block |
Shin et al. 2004 | 17 | 19 | Â | Combat | Combat vs. neutral scripts | Recall and imagine contents of script | PET | Block |
Symptom Provocation ROI Analyses (2) | ||||||||
Frewen et al. 2008 | 25 | 16 | Â | MVA+ | Trauma vs. neutral scripts | Listen to and image script | fMRI | Block |
Protopopescu et al. 2005 | 9 | 14 | Â | SA, PA+ | PTSD vs. neutral words | Read word | fMRI | Block |
Cognitive-Emotional Whole Brain Analyses (12) | ||||||||
Bremner et al. 2003 | 10 | Â | 11 | SA+ | Negative emotional vs. neutral word pairs | Declarative memory task | PET | Block |
Bremner et al. 2004 | 12 | 9 | Â | SA+ | Negative emotional vs. neutral words | Stroop task | PET | Block |
Brunetti et al. 2010 | 10 | Â | 10 | Assault | Negative emotional vs. neutral IAPS pictures | Visuo-attentional task | fMRI | Block |
Felmingham et al. 2010 | 23 | 21 | Â | Mixed | Fearful vs. neutral faces | Backward masking task | fMRI | Block |
Fonzo et al. 2010 | 12 | Â | 12 | IPV+ | Fearful vs. happy faces | Emotional face matching task | fMRI | Block |
Kim et al. 2008 | 12 | Â | 12 | Fire | Fearful vs. neutral faces | Same-different judgment task | fMRI | Event-related |
Sakamoto et al. 2005 | 16 | Â | 16 | Mixed | Traumatic vs. neutral images | View stimuli below perceptual threshold | fMRI | Block |
Shin et al. 2005 | 13 | 13 | Â | Combat, fire | Fearful vs. happy faces | Overt passive viewing task | fMRI | Block |
Thomaes et al. 2009 | 9 | Â | 9 | SA, PA+ | Negative words vs. baseline | Word classification task | fMRI | Event-related |
Whalley et al. 2009 | 16 | 16 | 16 | Mixed | Negative vs. neutral background pictures with neutral foreground pictures | Episodic memory retrieval task | fMRI | Event-related |
Williams et al. 2006 | 13 | Â | 13 | Mixed | Fearful vs. neutral faces | Overt fear perception task | fMRI | Block |
Hou et al. 2007 | Same Hou et al. 2007 article as the one listed above (in addition to symptom provocation coordinates, article reported coordinates from a short-term memory recall task) | |||||||
Cognitive-Emotional ROI Analyses (6) | ||||||||
Bryant et al. 2008 | 15 | Â | 15 | Mixed | Fearful vs. neutral faces | View stimuli below conscious threshold | fMRI | Block |
Phan et al. 2006 | 16 | 15 | Â | Combat | Negative vs. neutral IAPS pictures | View and rate pictures | PET | Block |
Rauch et al. 2000 | 8 | 8 | Â | Combat | Fearful vs. positive faces | Masked faces paradigm | fMRI | Block |
Felmingham et al. 2010 | Same as whole brain article above | |||||||
Fonzo et al. 2010 | Same as whole brain article above | |||||||
Williams et al. 2006 | Same as whole brain article above |