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Table 2 Structural neuroimaging findings in panic disorder [diffusion tensor imaging]

From: The role of the amygdala in the pathophysiology of panic disorder: evidence from neuroimaging studies

Study

Subjects

No. of subjects (female)

Mean age (SD)

Clinical state

Duration of illness (years)

Comorbid Depression

Comorbid Agoraphobia

Medication status

Field strength (Tesla)

Slice thickness (mm)

Amygdala

Hippocampus

Ventromedial Prefrontal cortex

Other brain regions

Han, 2008 [23]

PD

24 (10)

31.9 (6.8)

PDSS 9.5 (6.4)

3.6 (1.9)

HDRS-17 scores of PD patients were not different from those of HC subjects.

Not mentioned

Combination of antidepressants and anxiolytics

3.0

3.5

Not assessed

Not assessed

Left anterior cingulate, right posterior cingulate FA valueâ–²

Not assessed

 

HC

24 (10)

30.6 (5.1)

-

-

-

-

       
  1. Abbreviations: FA, fractional anisotropy; HC, healthy control; PD, panic disorder; PDSS, Panic Disorder Severity Scale; SD, standard deviation.