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Table 1 Demographic and clinical data of participants

From: Functional anomalies in healthy individuals with a first degree family history of major depressive disorder

 

FHN

(n = 14)

FHP

(n = 10)

MDD

(n = 14)

   
       

Χ2

df

P

Gender (female/male)

4/10

6/4

 

9/5

 

4.1

2/36

0.12

Handedness (right/left/ambidextrous)

14/0/0

8/2/0

 

12/1/1

 

5

4/34

0.3

 

Mean

SD

Mean

SD

Mean

SD

F

df

P

Age (years)

35

9.4

33

10

41.2

10.3

2.2

2/36

ns

Weight (kg)

74

18

63.3

5

73.6

13

1.9

2/36

ns

Illness duration (years)

-

-

-

-

16

10

-

-

-

HDRS score

0.7

0.9

4.8

5.3

24.8

5

125

2/36

< 0.001a

Age of onset

-

-

-

-

25

11

-

-

-

 

Median

MR

Median

MR

Median

MR

4.7

df

P

Alcohol intake per week (g)

16

16

60

26

28

18

4.6

2/36

ns

Cigarettes per day

0

15

1

23.5

0

21

5.7

2/36

ns

  1. aThere was a difference between the MDD patients and either the FHN (P < 0.001) or the FHP (P < 0.001) subjects in the HDRS; bF-score from analysis of variance. df: degrees of freedom; MDD: patients with major depressive disorder; FHN: healthy participants without family history of MDD; FHP: healthy participants with family history of MDD; HDRS: Hamilton Depression Rating Scale for Depression; ns: not significant; SD: standard deviation, Χ2: Chi-squared score, MR: Mean Rank