Skip to main content

Table 4 Psychophysiological interaction analysis

From: An fMRI study of unconditioned responses in post-traumatic stress disorder

Seed MNIa, peak x, y, z Z-score Size, voxels Cluster Pvalue, FWEb Regionc
Left putamen      
   TENCd > PTSDe -44, -12, -16 4.65 295 0.01 Left temporal lobe
  (-32, 0, -30) 4.01    Left parahippocampal lobe/amygdala
  (-30, -10, -22) 3.72    Left parahippocampal gyrus
   PTSD > TENC No significant differences    
Right putamen      
   TENC > PTSD -30, 0, -32 4.54 248 0.019 Left temporal lobe wm/amygdala
  (-48, 8, -30) 3.97    Left middle temporal gyrus
  (-56, 4, -26) 3.44    Left middle temporal gyrus
   PTSD > TENC No significant differences    
Left middle frontal gyrus      
   TENC > PTSD No significant differences    
   PTSD > TENC No significant differences    
Left parahippocampal gyrus      
   TENC > PTSD 44, -34, 42 4.45 449 0.001 Right inferior parietal lobule
  48, -38, 50 -4.27    Right inferior parietal lobule
  52, -26, 50 -3.77    Right postcentral gyrus
  -10, 66, 10 4.42 263 0.017 Left medial frontal gyrus
  (-14, 62, 0) -4.06    Left medial frontal gyrus
  (-8, 62, 18) -3.45    Left medial frontal gyrus
  34, -20, 68 4.37 487 0.001 Right precentral gyrus
  (34, -16, 46) -4.14    Right precentral gyrus
  (22, -16, 74) -4.12    Right precentral gyrus
   PTSD > TENC No significant differences    
  1. aMontreal Neurological Institute.
  2. bFamily-wise error.
  3. cRegions were identified based on nearest gray matter.
  4. dPost-traumatic stress disorder.
  5. eTrauma-exposed normal control.