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Table 2 Summary of the studies which included N100 component

From: Event-related potential studies of post-traumatic stress disorder: a critical review and synthesis

Study Subjects Paradigm Results
[31] 12 combat PTSD veterans
6 normal controls
Four tones intensity paradigm No difference in N1 amplitude
[17] 20 Israeli combat veterans with PTSD
20 without PTSD
Visual oddball, trauma related
neutral stimuli
Combat-related pictures elicited enhanced N1 amplitude in PTSD group.
Prolonged N1 latencies and reaction times to target stimuli in PTSD patients.
[56] 16 medicated, 9 un-medicated PTSD
10 healthy veterans
Auditory three-tone oddball Longer N100 latencies in un-medicated PTSD patients compared to the medicated PTSD and healthy controls.
[51] 11 prisoners of war Checkerboard reversal Larger N75 amplitudes
[39] 11 PTSD survivors of a ship fire
9 psychiatric controls from the same ship
Auditory word and non-word oddball Increased N1 latency to standard tones;
Larger amplitude to emotionally meaningful words.
[25] 13 females with sexual assault PTSD
16 healthy controls
Auditory oddball No difference in N100 amplitude and latency
[28] 17 civil PTSD
17 healthy controls
Auditory oddball No difference in N100 amplitude or latency
[30] 36 civil PTSD 20 healthy 10 depressed 8 alcoholics 2000-Hz tone presented in increasing intensities Increased N100 amplitudes
[38] 15 civil PTSD
15 controls
Visual presentation of angry alternating with neutral faces Larger N110 to the angry compared to the neutral faces in the control group.
Smaller and later N100 in PTSD subjects.
[35] 10 civil PTSD
10 controls
Auditory oddball Larger N100 amplitude
[42] 19 PTSD 99 Alcohol dependence 16 personality disorder 25 anxiety or mood disorder Visual presentation of happy, sad, and neutral faces Larger N1 amplitudes to sad stimuli in frontotemporal leads in PTSD patients.
[57] 16 civil PTSD
16 schizophrenia
16 control subjects
Auditory Oddball No difference in N1 amplitude and latency
[36] 14 PTSD [mixed etiologies]
12 controls
Auditory Oddball No difference in N100 amplitude