Characteristics | Kieseppä et al.[18] | Blood et al.[24] | Zhu et al.[58] | Wu et al.[25] | Korgaonkar et al.[60] | Jia et al.[26] | Abe et al.[59] |
---|---|---|---|---|---|---|---|
Number of patients | 16 | 22 | 25 | 23 | 29 | 52 | 21 |
Number of controls | 20 | 22 | 25 | 21 | 39 | 52 | 42 |
Mean age of patients, years | 48.4 | 36.3 | 20.6 | 31.4 | 40.5 | 34.5 | 48.1 |
Mean age of controls, years | 42 | 35.3 | 20.3 | 30.4 | 29.6 | 37.1 | 48 |
Patient sex, % female | 87.5 | 54.5 | 60 | 65.5 | 58.7 | 51.9 | 47.6 |
Control sex, % female | 50 | 54.5 | 60 | 56.5 | 53.8 | 54 | 47.6 |
Late-life depression | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Major depressive disorder | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Anxiety in patients (0 = no, 1 = yes) | NA | 0 | 0 | 0 | NA | 0 | 0 |
Treatment, % patients receiving medication at time of study | 81 | 31.8 | 0 | 0 | 0 | 0 | 90.5 |
Mean illness duration, years | 14.1 | NA | 13.6 | 2.2 | NA | 3.3 | 6 |
Mean BDI score | 26.3 | NA | NA | NA | NA | NA | NA |
Hamilton score | NA | NA | NA | 21.8 | 19.1 | 23 | 9.2 |
IDS-SR score | NA | 36 | NA | NA | NA | NA | NA |
Mean CES-D score | NA | NA | 35.48 | NA | NA | NA | NA |
Illness severity | 2 | 2 | 3 | 3 | 3 | 3 | 1 |